Forschung
STARTSEITEDie NMR-Relaxation ist eine Methode zur Untersuchung physikalischer und chemischer Eigenschaften von Proben unterschiedlichster Natur: von biologischen Geweben bis hin zu synthetischen Polymeren. Die NMR-Relaxation ist aufgrund ihrer Nicht-Invasivität, einfachen Probenvorbereitung, Mobilität (autarker Einstz), hohen Empfindlichkeit und Analysegeschwindigkeit für die Forschung sehr attraktiv und findet in vielen Branchen praktischen Anwendungen.
Hauptparameter, die im niedrigaufgelösten(?) NMR-Experiment gemessen werden, sind die Relaxationszeiten (T1 und T2) sowie die Amplituden der einzelnen Komponenten der Relaxationssignale bei der Untersuchung von Mehrphasensystemen. Der NMR-Analysator Spin Track ermöglicht die Durchführung sowohl klassischer Pulssequenzen wie FID, Solid Echo und CPMG in T2-Experimenten, der Sättigungswiederherstellungssequenz in T1-Experimenten als auch spezifischer Pulssequenzen wie Goldman-Shen-Sequenz und DQ-Filter, die in komplexeren Experimenten zur Untersuchung des Spindiffusionsprozesses verwendet werden.
Im letzten Jahrzehnt haben wir Spezialisten in physikalischer Chemie und technischen Anwendungen der NMR ausgebildet - https://cellulose-research.com/
Wir den Bereich unserer Anwendungsentwicklung durch die Zusammenarbeit mit den wissenschaftlich-technisch hervorragenden Teams der METU (Middle East Technical University, Ankara, Türkei), UMB (University of Maryland, Baltimore, USA) und VSCT (University of Chemistry and Technology, Prag, Tschechische Republik) erfolgreich weiterentwickeln. Es wurden dabei in unterschiedlichen Anwendungen neue TD-NMR-Entwicklungen für die Lebensmittel-, Pharma- und Polymerindustrie gefunden und umgesetzt. Diese werden heute bereits erfolgreich angewendet.
Insbesondere für pharmazeutische Anwendungen haben wir große Anstrengungen unternommen, um erschwingliche Low-Field-NMR-Geräte zu entwickeln, die qualitativ hochwertige Messungen in einem breiten Probentemperaturbereich (von –50 °C bis +200 °C) durchführen und verschiedene Probenröhrchen und Impfstofffläschchen aufnehmen können (Abmessungen bis 40 mm). Für die Online-Überwachung der Proteinaggregation und -reinheit bieten wir die Möglichkeit der Überwachung der Relaxationszeiten im Durchfluss mit Raten von bis zu 100 ml pro Minute.
Klicken Sie hier, wenn Sie einige Original-Forschungsarbeiten erkunden möchten, die mit dem Spin Track erstellt wurden.
-
Unravelling temperature-dependent molecular changes in hydrated wheat and maize starches using 1H time-domain NMR
Jana van Rooyen, Leonid Grunin, Mecit Oztop, Danuta Kruk, Marena Manley
Journal of Food Engineering, 375, 112041, 2024
DOI: 10.1016/j.jfoodeng.2024.112041
URL: https://www.sciencedirect.com/science/article/pii/S0260877424001079?via%3Dihub -
Correlation of low field nuclear magnetic resonance relaxation with composition and glass transition of hard candies
Baris Ozel, Berkay Berk, Sirvan Sultan Uguz, Leonid Grunin, Mecit Halil Oztop
Frontiers in Food Science and Technology, 4, 2024
DOI: 10.3389/frfst.2024.1263380
URL: https://www.frontiersin.org/articles/10.3389/frfst.2024.1263380/full -
Influence of multiple parameters on the crystallinity of dairy powders
Selen Guner San, Leonid Grunin, Ozlem Kaner, Gulum Sumnu, Mecit Halil Oztop
International Dairy Journal, 147, 105782, 2023
DOI: 10.1016/j.idairyj.2023.105782
URL: https://www.sciencedirect.com/science/article/abs/pii/S0958694623002017?via%3Dihub -
Influence of gas penetrans on polyethylene crystallinity observed by low field NMR
Patrik Schneider, Tomáš Chaloupka, Leonid Grunin, Juraj Kosek
Polymer Testing, 127(7), 108174, 2023
DOI: 10.1016/j.polymertesting.2023.108174
URL: https://www.sciencedirect.com/science/article/pii/S0142941823002544?via%3Dihub -
Time-Domain NMR Techniques in Cellulose Structure Analysis
Leonid Grunin, Maria Ivanova, Veronika Schiraya, Tatiana Grunina
Applied Magnetic Resonance, 2023
DOI: 10.1007/s00723-023-01600-4
URL: https://link.springer.com/article/10.1007/s00723-023-01600-4 -
Nanocellulose-Based Thermoplastic Polyurethane Biocomposites with Shape Memory Effect
Marina Gorbunova, Leonid Grunin, Robert H. Morris, Arina Imamutdinova
Journal of Composites Science, 7(4), 168, 2023
DOI: 10.3390/jcs7040168
URL: https://www.mdpi.com/2504-477X/7/4/168 -
Molecular Dynamics of Jelly Candies by Means of Nuclear Magnetic Resonance Relaxometry
Danuta Kruk, Leonid Grunin, Aleksandra Stankiewicz, Karol Kołodziejski, Esmanur Ilhan, Mecit Halil Oztop
Molecules, 28(5), 2230, 2023
DOI: 10.2139/ssrn.4361225
URL: https://www.mdpi.com/1420-3049/28/5/2230 -
Influence of Multiple Parameters on the Crystallinity of Dairy Powders
Selen Guner, Leonid Grunin, S. Gulum Sumnu, Ozlem Kaner, Mecit Oztop
SSRN Electronic Journal, 2023
DOI: 10.2139/ssrn.4361225
URL: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4361225 -
Effect of Different Syrup Types on Turkish Delights (Lokum): A TD-NMR Relaxometry Study
Pelin Poçan, Leonid Grunin, Mecit Halil Oztop
ACS Food Science & Technology, 2(12), 2022
DOI: 10.1021/acsfoodscitech.2c00222
URL: https://pubs.acs.org/doi/10.1021/acsfoodscitech.2c00222 -
Ultrasound-assisted co-precipitation synthesis of GdFeO3 nanoparticles: structure, magnetic and MRI contrast properties
Yamen Albadi, Maria S. Ivanova, Leonid Y. Grunin, Rodion A. Makarin, Aleksei S. Komlev, Maria I. Chebanenko, Vladimir N. Nevedomskyi, Vadim I. Popkov
Physical Chemistry Chemical Physics, 24(47), 2022
DOI: 10.1039/D2CP03688F
URL: https://pubs.rsc.org/en/content/articlelanding/2022/CP/D2CP03688F -
Non-Conventional Time Domain (TD)-NMR Approaches for Food Quality: Case of Gelatin-Based Candies as a Model Food
Sirvan Sultan Uguz, Baris Ozel, Leonid Grunin, Emin Burcin Ozvural, Mecit Halil Oztop
Molecules, 27(19), 6745, 2022
DOI: 10.3390/molecules27196745
URL: https://www.mdpi.com/1420-3049/27/19/6745 -
Exploring the Crystallinity of Turkish Delights by Using Magic Sandwich Echo Sequence (MSE)
Pelin Poçan, Leonid Grunin, Mecit Halil Oztop
12th Conference on Fast Field Cycling NMR Relaxometry, on 13-15th of July 2022, University of Cambridge, Murray Edward's College
https://ffcrelax.ceb.cam.ac.uk/ -
Use of Magic Sandwich Echo and Fast Field Cycling NMR Relaxometry on Honey Adulteration with Corn Syrup
Berkay Berk, Cagri Cavdaroglu, Leonid Grunin, Ioan Ardelean, Danuta Kruk, Bekir G. Mazi, Mecit H. Oztop
Journal of the Science of Food and Agriculture, 102(7), 2022
DOI: 10.1002/jsfa.11606
URL: https://onlinelibrary.wiley.com/doi/10.1002/jsfa.11606 -
Nuclear Magnetic Resonance (NMR) study of Palm Kernel Stearin: Effects of cooling rate on crystallization behaviour
Ilhami Okur, Baris Ozel, Derya Ucbas, Leonid Grunin, Purlen Sezer Okur, Hami Alpas, Semra Ide, Mecit Halil Oztop
Lebensmittel-Wissenschaft und-Technologie, 155(5), 113001, 2022
DOI: 10.1016/j.lwt.2021.113001
URL: https://www.sciencedirect.com/science/article/pii/S002364382102154X?via%3Dihub -
The effect of separation of blocks on the crystallization kinetics and phase composition of poly(butylene adipate) in multi-block thermoplastic polyurethanes
Marina A. Gorbunova, Evgenii V. Komov, Leonid Yu. Grunin, Mariya S. Ivanova, Ainur F. Abukaev, Arina M. Imamutdinova, Dimitri A. Ivanov, Denis V. Anokhin
Physical Chemistry Chemical Physics, 24(2), 2022
DOI: 10.1039/d1cp04684e
URL: https://pubs.rsc.org/en/content/articlelanding/2022/CP/D1CP04684E -
Features of the Gas-Permeable Crystalline Phase of Poly-2,6-Dimethylphenylene Oxide
Alexander Yu. Alentiev, Ivan S. Levin, Nikolay A. Belov, Roman Yu. Nikiforov, Sergey V. Chirkov, Denis A. Bezgin, Victoria E. Ryzhikh, Julia V. Kostina, Victor P. Shantarovich, Leonid Yu. Grunin
Polymers, 14(1), 120, 2022
DOI: 10.3390/polym14010120
URL: https://www.mdpi.com/2073-4360/14/1/120 -
An investigation of functional quality characteristics and water interactions of navy bean, chickpea, pea, and lentil flours
Ozan Tas, Ulku Ertugrul, Leonid Grunin, Mecit Halil Oztop
Legume Science, 4(1), e136, 2022
DOI: 10.1002/leg3.136
URL: https://onlinelibrary.wiley.com/doi/10.1002/leg3.136 -
Investigation of the Hydration Behavior of Different Sugars by Time Domain-NMR
Ozan Tas, Ulku Ertugrul, Leonid Grunin, Mecit Halil Oztop
Foods, 11(8), 1148, 2022
DOI: 10.3390/foods11081148
URL: https://www.mdpi.com/2304-8158/11/8/1148 -
The Influence of Co-Precipitation Technique on the Structure, Morphology and Dual-Modal Proton Relaxivity of GdFeO3 Nanoparticles
Yamen Albadi, Maria S. Ivanova, Leonid Y. Grunin, Kirill D. Martinson, Maria I. Chebanenko, Svetlana G. Izotova, Vladimir N. Nevedomskiy, Rufat S. Abiev, Vadim I. Popkov
Inorganics, 9(5), 39, 2021
DOI: 10.3390/inorganics9050039
URL: https://www.mdpi.com/2304-6740/9/5/39 -
Use of Solid Echo Sequence to Monitor Crystallization Kinetics of Mono and Di-Saccharides
Selen Guner, Leonid Grunin, S. Gulum Sumnu, Mecit Halil Oztop
Food Biophysics, 16(4), 2021
DOI: 10.1007/s11483-021-09688-6
URL: https://link.springer.com/article/10.1007/s11483-021-09688-6 - A non-conventional TD-NMR approach to monitor honey crystallization and melting
Berkay Berk, Leonid Grunin, Mecit H. Oztop
Journal of Food Engineering, 292, 2021.
DOI: 10.1016/j.jfoodeng.2020.110292
URL: https://www.sciencedirect.com/science/article/abs/pii/S0260877420303800?via%3Dihub - Thermodynamics of Adsorption in a Cellulose–Water System
Yu.B. Grunin, M.S. Ivanova, D.S. Masas, L.Yu. Grunin
Russian Journal of Physical Chemistry A, 94(4), 2020.
DOI: 10.1134/S0036024420040056
URL: https://link.springer.com/article/10.1134%2FS0036024420040056 - Features of the Structural Organization and Sorption Properties of Cellulose
Yu.B. Grunin, L.Yu. Grunin, M.S. Ivanova, D.S. Masas
Fibre Chemistry, 51(5), 2020.
DOI: 10.1007/s10692-020-10106-9
URL: https://link.springer.com/article/10.1007/s10692-020-10106-9 - Characteristics of Supramolecular Rearrangements in Cellulose in the Processes of its Wetting and Desorption
Yu.B. Grunin, L.Yu. Grunin, M.S. Ivanova, D.S. Masas
Fibre Chemistry, 52(1), 2020.
DOI: 10.1007/s10692-020-10142-5
URL: https://link.springer.com/article/10.1007/s10692-020-10142-5 - Cellulose–water system’s state analysis by proton nuclear magnetic resonance and sorption measurements
Yu.B. Grunin, L.Yu. Grunin, V.Yu. Schiraya, M.S. Ivanova, D.S. Masas
Bioresources and Bioprocessing, 7(41), 2020.
DOI: 10.1186/s40643-020-00332-8
URL: https://link.springer.com/article/10.1186/s40643-020-00332-8 - Jet-cooked papermaking starches studied using 1H NMR-relaxometry and viscom
J.P. Raunio, E. Nikolskaya, H. Yrjö
Nordic Pulp and Paper Research Journal, 2020.
DOI: 10.1515/npprj-2019-0092
URL: https://www.degruyter.com/document/doi/10.1515/npprj-2019-0092/html - Real-time measurement system for determining metal concentrations in water-intensive processes
E. Nikolskaya, M. Liukkonen, H. Yrjö
Open Engineering, 2020.
DOI: 10.1515/eng-2020-0063
URL: https://www.degruyter.com/document/doi/10.1515/epoly-2020-0063/html - Time-Domain NMR in Characterization of Liquid Fuels: A Mini-Review
E. Nikolskaya, H. Yrjö
Energy & Fuels, 2020.
DOI: 10.1021/acs.energyfuels.0c01464
URL: https://pubs.acs.org/doi/abs/10.1021/acs.energyfuels.0c01464 - The use of 1H-NMR Relaxation Times of Water Adsorbed on Soils to Monitor Environment Pollution
Leonid Grunin, Ekaterina Nikolskaya, John Edwards
Air, Soil and Water Research, 6(1), 2020.
DOI: 10.1177/ASWR.S12406
URL: https://bioone.org/journals/air-soil-and-water-research/volume-6/issue-1/ASWR.S12406/The-use-of-1H-NMR-Relaxation-Times-of-Water-Adsorbed/10.1177/ASWR.S12406.full - The Nature of the Supramolecular Structural Variation and Hydrophilic Properties of Cellulose during Water Sorption
Yu.B. Grunin, M.S. Ivanova, D.S. Masas, L.Yu. Grunin
Biophysics, 64(6), 2019.
DOI: 10.1134/S0006350919060071
URL: https://link.springer.com/article/10.1134%2FS0006350919060071 - Solids Content of Black Liquor Measured by Online Time-Domain NMR
E. Nikolskaya, P. Janhunen, M. Haapalainen, H. Yrjö
Applied Sciences, 2019.
DOI: 10.3390/app9102169
URL: https://www.mdpi.com/2076-3417/9/10/2169 - Molecular Properties of Fatty Acid Mixtures Estimated by Online Time-Domain NMR
E. Nikolskaya, H. Yrjö
Applied Magnetic Resonance, 2019.
DOI: 10.1007/s00723-018-1046-6
URL: https://link.springer.com/article/10.1007/s00723-018-1046-6 - Flow Water Proton NMR: In-Line Process Analytical Technology for Continuous Biomanufacturing
Marc B. Taraban, Katharine T. Briggs, Peter Merkel, Y. Bruce Yu
Analytical Chemistry, 91, 2019.
DOI: 10.1021/acs.analchem.9b02622
URL: https://pubs.acs.org/doi/10.1021/acs.analchem.9b02622 - Exploring the crystallinity of different powder sugars through solid echo and magic sandwich echo sequences
Leonid Grunin, Mecit Halil Oztop, Selen Guner, Saadet Fatma Baltaci
Magnetic Resonance in Chemistry, 57, 2019.
DOI: 10.1002/mrc.4866
URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/mrc.4866 - Dispersion Peculiarities of Crystalline Cellulose Upon its Moistening
Yu.B. Grunin, L.Yu. Grunin, L.S. Gal’braikh, N.N. Sheveleva, D.S. Masas
Fibre Chemistry, 49(5), 2018.
DOI: 10.1007/s10692-018-9890-6
URL: https://link.springer.com/article/10.1007/s10692-018-9890-6 - On-line monitoring of cationic starch gelatinization and retrogradation by 1H NMR-relaxometry
J.P. Raunio, E. Nikolskaya, H. Yrjö
Nordic Pulp and Paper Research Journal, 2018.
DOI: 10.1515/npprj-2018-0010
URL: https://www.degruyter.com/document/doi/10.1515/npprj-2018-0010/html - Determination of Carbon Chain Lengths of Fatty Acid Mixtures by Time Domain NMR
E. Nikolskaya, H. Yrjö
Applied Magnetic Resonance, 2018.
DOI: 10.1007/s00723-017-0953-2
URL: https://link.springer.com/article/10.1007/s00723-017-0953-2 - Illustration of inversion‐recovery and Carr‐Purcell‐Meiboom‐Gill sequences by the determination of ethanol content in alcoholic beverages
Yves Gossuin, Quoc L. Vuong, Leonid Grunin, Laurence Van Nedervelde, Anne Pietercelie
Concepts Magn Reson Part A. 2018. 46A: e21460.
DOI: 10.1002/cmr.a.21460
URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/cmr.a.21460 - Physico-Chemical Changes of Composite Whey Protein Hydrogels in Simulated Gastric Fluid Conditions
Baris Ozel, Ozlem Aydin, Ozlem Aydin, Leonid Grunin, Mecit H. Oztop
Journal of Agricultural and Food Chemistry, 66(36), 2018.
DOI: 10.1021/acs.jafc.8b02829
URL: https://pubs.acs.org/doi/10.1021/acs.jafc.8b02829 - The character of changes in the cellulose supramolecular structure during hydration
Yu.B. Grunin, L.Yu. Grunin, N.N. Sheveleva, S.V. Fedosov, V.G. Kotlov
Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Teknologiya Tekstil'noi Promyshlennosti, 1(2), 2017. URL: https://www.researchgate.net/publication/321712673_The_character_of_changes_in_the_cellulose_supramolecular_structure_during_hydration - An NMR relaxation and spin diffusion study of cellulose structure during water adsorption
L.Y. Grunin, Y.B. Grunin, E.A. Nikolskaya, N.N. Sheveleva, I.A. Nikolaev
Biophysics, 62(2), 2017.
DOI: 10.1134/S0006350917020087
URL: https://link.springer.com/article/10.1134/S0006350917020087 - Novel online solution for the measurement of metal ions in water intensive processes
E. Nikolskaya, M. Liukkonen, H. Yrjö
Conference: Finnish Conference of Environmental Sciences 2017 (FCES'17) At: Joensuu, Finland. URL: https://www.researchgate.net/publication/317659409_Novel_online_solution_for_the_measurement_of_metal_ions_in_water_intensive_processes - Effect of different polysaccharides on swelling of composite whey protein hydrogels: A low field (LF) NMR relaxometry study
Baris Ozel, Sirvan S. Uguz, Mete Kilercioglu, Leonid Grunin, Mecit H. Oztop
Journal of Food Process Engineering, 40(3), 2017.
DOI: 10.1111/jfpe.12465
URL: https://doi.org/10.1111/jfpe.12465 - Proton magnetic relaxation study of the thermodynamic characteristics of water adsorbed by cellulose fibers
Y.B. Grunin, L.Y. Grunin, D.S. Masas, V.I. Talantsev, N.N. Sheveleva
Russian Journal of Physical Chemistry A, 90(11), 2016.
DOI: 10.1134/S003602441611008X
URL: https://link.springer.com/article/10.1134%2FS003602441611008X - Structure and Sorption Characteristics of Nanocrystallites of Chitosan
Yu.B. Grunin, L.S. Gal’braikh, S.V. Levitin, D.S. Masas
Fibre Chemistry, 48(4), 2016.
DOI: 10.1007/s10692-017-9785-y
URL: https://link.springer.com/article/10.1007/s10692-017-9785-y - Water Content Analysis of Sludge Using NMR Relaxation Data and Independent Component Analysis
M. Liukkonen, E. Nikolskaya, J. Selin, H. Yrjö
Conference: 2016 9th EUROSIM Congress on Modelling and Simulation (Eurosim 2016) At: Oulu, Finland.
DOI: 10.3384/ecp17142317
URL: https://ep.liu.se/ecp/article.asp?issue=142%26article=46 -
Free and constrained amorphous phases in polyethylene: Interpretation of 1H NMR and SAXS data over a broad range of crystallinity
Josef Chmelař, Richard Pokorný, Patrik Schneider, Klará Smolná, Petr Bělský, Juraj Kosek
Polymer, 58, 2015.
DOI: 10.1016/j.polymer.2014.12.036
URL: https://doi.org/10.1016/j.polymer.2014.12.036
Wenn Sie zusätzliche Informationen oder Diskussionsbedarf benötigen, nutzen Sie Feedback oder kontaktieren Sie uns über info@resonance-systems.de