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NMR relaxation is an informative method for studying physical and chemical properties of a wide range of samples which have different nature: from biological tissues to artificial polymers. The NMR relaxation with its non-invasiveness, minimal sample preparation, mobility, high sensitivity, speed of analysis is very attractive for researches and finds practical application in many industries.

Main parameters measured in the low-resolution NMR experiment are the relaxation times T1 and T2, as well as the amplitudes of the individual components of the relaxation signals in the study of multiphase systems. NMR analyzer Spin Track allows one carrying out both classical pulse sequences such as FID, Solid Echo and CPMG in T2 experiments, Saturation recovery sequence in T1 experiments, and also specific pulse sequences such as Goldman-Shen sequence and DQ-filter, which are used in more complex experiments on studying spin diffusion process.

Our Own Scientific Mission

In recent decade we educate specialists in Physical Chemistry and Technical applications of NMR - https://cellulose-research.com/

We have significantly widened the area of our application development, cooperating with fantastic teams of METU (Middle East Technical University, Ankara, Turkey), UMB (University of Maryland, Baltimore, USA) and VSCT (University of Chemistry and Technology, Prague, Czech Republic) to bring new TD-NMR visions for Food and Pharma and Polymer industries.

Especially for pharmaceutical applications we have invested lots of efforts to develop affordable Low-Field NMR machines capable to do high quality measurements with wide range of sample temperatures (from –50° to +200 °C), accommodate various sample tubes and vaccines vials with dimensions up to 40 mm. For online monitoring of proteins aggregation and purity we offer capability of relaxation times monitoring in flow with rates of up to 100 ml per minute.

Click here, if you want to explore some original research papers made using the Spin Track.
  • Advancing Pharmaceutical Security: Noninvasive Detection of Falsified Vaccines and Drugs Using wNMR
    Marc Taraban, Katharine Briggs, Pratima Karki, Leonid Grunin, Y. Yu
    Pharmaceutical Research, 42, 987–1001, 2025
    DOI: 10.1007/s11095-025-03880-w
    URL: https://doi.org/10.1007/s11095-025-03880-w
  • Universal H Spin–Lattice NMR Relaxation Features of Sugar—A Step towards Quality Markers
    Hafiz Imran Fakhar, Adam Kasparek, Karol Kołodziejski, Leonid Grunin, Mecit Öztop, Muhammad Qasim Hayat, Hussnain Janjua, Danuta Kruk
    Molecules, 29, 2422, 2024
    DOI: 10.3390/molecules29112422
    URL: https://doi.org/10.3390/molecules29112422
  • Investigating the crystallinity of hard candies prepared and stored at different temperatures with low field‐NMR relaxometry
    Sena Kuzu, Barış Özel, Sirvan Uguz, Sarper Dogdu, Mehmet Marangoz, Leonid Grunin, Mecit Oztop
    Journal of the Science of Food and Agriculture, 105, 489–497, 2024
    DOI: 10.1002/jsfa.13847
    URL: https://doi.org/10.1002/jsfa.13847
  • Unravelling temperature-dependent molecular changes in hydrated wheat and maize starches using 1H time-domain NMR
    Jana van Rooyen, Leonid Grunin, Mecit Oztop, Danuta Kruk, Marena Manley
    Journal of Food Engineering, 375, 112041, 2024
    DOI: 10.1016/j.jfoodeng.2024.112041
    URL: https://www.sciencedirect.com/science/article/pii/S0260877424001079?via%3Dihub
  • Correlation of low field nuclear magnetic resonance relaxation with composition and glass transition of hard candies
    Baris Ozel, Berkay Berk, Sirvan Sultan Uguz, Leonid Grunin, Mecit Halil Oztop
    Frontiers in Food Science and Technology, 4, 2024
    DOI: 10.3389/frfst.2024.1263380
    URL: https://www.frontiersin.org/articles/10.3389/frfst.2024.1263380/full
  • Influence of multiple parameters on the crystallinity of dairy powders
    Selen Guner San, Leonid Grunin, Ozlem Kaner, Gulum Sumnu, Mecit Halil Oztop
    International Dairy Journal, 147, 105782, 2023
    DOI: 10.1016/j.idairyj.2023.105782
    URL: https://www.sciencedirect.com/science/article/abs/pii/S0958694623002017?via%3Dihub
  • Influence of gas penetrans on polyethylene crystallinity observed by low field NMR
    Patrik Schneider, Tomáš Chaloupka, Leonid Grunin, Juraj Kosek
    Polymer Testing, 127(7), 108174, 2023
    DOI: 10.1016/j.polymertesting.2023.108174
    URL: https://www.sciencedirect.com/science/article/pii/S0142941823002544?via%3Dihub
  • Time-Domain NMR Techniques in Cellulose Structure Analysis
    Leonid Grunin, Maria Ivanova, Veronika Schiraya, Tatiana Grunina
    Applied Magnetic Resonance, 2023
    DOI: 10.1007/s00723-023-01600-4
    URL: https://link.springer.com/article/10.1007/s00723-023-01600-4
  • Nanocellulose-Based Thermoplastic Polyurethane Biocomposites with Shape Memory Effect
    Marina Gorbunova, Leonid Grunin, Robert H. Morris, Arina Imamutdinova
    Journal of Composites Science, 7(4), 168, 2023
    DOI: 10.3390/jcs7040168
    URL: https://www.mdpi.com/2504-477X/7/4/168
  • Molecular Dynamics of Jelly Candies by Means of Nuclear Magnetic Resonance Relaxometry
    Danuta Kruk, Leonid Grunin, Aleksandra Stankiewicz, Karol Kołodziejski, Esmanur Ilhan, Mecit Halil Oztop
    Molecules, 28(5), 2230, 2023
    DOI: 10.2139/ssrn.4361225
    URL: https://www.mdpi.com/1420-3049/28/5/2230
  • Influence of Multiple Parameters on the Crystallinity of Dairy Powders
    Selen Guner, Leonid Grunin, S. Gulum Sumnu, Ozlem Kaner, Mecit Oztop
    SSRN Electronic Journal, 2023
    DOI: 10.2139/ssrn.4361225
    URL: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4361225
  • Effect of Different Syrup Types on Turkish Delights (Lokum): A TD-NMR Relaxometry Study
    Pelin Poçan, Leonid Grunin, Mecit Halil Oztop
    ACS Food Science & Technology, 2(12), 2022
    DOI: 10.1021/acsfoodscitech.2c00222
    URL: https://pubs.acs.org/doi/10.1021/acsfoodscitech.2c00222
  • Ultrasound-assisted co-precipitation synthesis of GdFeO3 nanoparticles: structure, magnetic and MRI contrast properties
    Yamen Albadi, Maria S. Ivanova, Leonid Y. Grunin, Rodion A. Makarin, Aleksei S. Komlev, Maria I. Chebanenko, Vladimir N. Nevedomskyi, Vadim I. Popkov
    Physical Chemistry Chemical Physics, 24(47), 2022
    DOI: 10.1039/D2CP03688F
    URL: https://pubs.rsc.org/en/content/articlelanding/2022/CP/D2CP03688F
  • Non-Conventional Time Domain (TD)-NMR Approaches for Food Quality: Case of Gelatin-Based Candies as a Model Food
    Sirvan Sultan Uguz, Baris Ozel, Leonid Grunin, Emin Burcin Ozvural, Mecit Halil Oztop
    Molecules, 27(19), 6745, 2022
    DOI: 10.3390/molecules27196745
    URL: https://www.mdpi.com/1420-3049/27/19/6745
  • Exploring the Crystallinity of Turkish Delights by Using Magic Sandwich Echo Sequence (MSE)
    Pelin Poçan, Leonid Grunin, Mecit Halil Oztop
    12th Conference on Fast Field Cycling NMR Relaxometry, on 13-15th of July 2022, University of Cambridge, Murray Edward's College
    https://ffcrelax.ceb.cam.ac.uk/
  • Use of Magic Sandwich Echo and Fast Field Cycling NMR Relaxometry on Honey Adulteration with Corn Syrup
    Berkay Berk, Cagri Cavdaroglu, Leonid Grunin, Ioan Ardelean, Danuta Kruk, Bekir G. Mazi, Mecit H. Oztop
    Journal of the Science of Food and Agriculture, 102(7), 2022
    DOI: 10.1002/jsfa.11606
    URL: https://onlinelibrary.wiley.com/doi/10.1002/jsfa.11606
  • Nuclear Magnetic Resonance (NMR) study of Palm Kernel Stearin: Effects of cooling rate on crystallization behaviour
    Ilhami Okur, Baris Ozel, Derya Ucbas, Leonid Grunin, Purlen Sezer Okur, Hami Alpas, Semra Ide, Mecit Halil Oztop
    Lebensmittel-Wissenschaft und-Technologie, 155(5), 113001, 2022
    DOI: 10.1016/j.lwt.2021.113001
    URL: https://www.sciencedirect.com/science/article/pii/S002364382102154X?via%3Dihub
  • The effect of separation of blocks on the crystallization kinetics and phase composition of poly(butylene adipate) in multi-block thermoplastic polyurethanes
    Marina A. Gorbunova, Evgenii V. Komov, Leonid Yu. Grunin, Mariya S. Ivanova, Ainur F. Abukaev, Arina M. Imamutdinova, Dimitri A. Ivanov, Denis V. Anokhin
    Physical Chemistry Chemical Physics, 24(2), 2022
    DOI: 10.1039/d1cp04684e
    URL: https://pubs.rsc.org/en/content/articlelanding/2022/CP/D1CP04684E
  • Features of the Gas-Permeable Crystalline Phase of Poly-2,6-Dimethylphenylene Oxide
    Alexander Yu. Alentiev, Ivan S. Levin, Nikolay A. Belov, Roman Yu. Nikiforov, Sergey V. Chirkov, Denis A. Bezgin, Victoria E. Ryzhikh, Julia V. Kostina, Victor P. Shantarovich, Leonid Yu. Grunin
    Polymers, 14(1), 120, 2022
    DOI: 10.3390/polym14010120
    URL: https://www.mdpi.com/2073-4360/14/1/120
  • An investigation of functional quality characteristics and water interactions of navy bean, chickpea, pea, and lentil flours
    Ozan Tas, Ulku Ertugrul, Leonid Grunin, Mecit Halil Oztop
    Legume Science, 4(1), e136, 2022
    DOI: 10.1002/leg3.136
    URL: https://onlinelibrary.wiley.com/doi/10.1002/leg3.136
  • Investigation of the Hydration Behavior of Different Sugars by Time Domain-NMR
    Ozan Tas, Ulku Ertugrul, Leonid Grunin, Mecit Halil Oztop
    Foods, 11(8), 1148, 2022
    DOI: 10.3390/foods11081148
    URL: https://www.mdpi.com/2304-8158/11/8/1148
  • The Influence of Co-Precipitation Technique on the Structure, Morphology and Dual-Modal Proton Relaxivity of GdFeO3 Nanoparticles
    Yamen Albadi, Maria S. Ivanova, Leonid Y. Grunin, Kirill D. Martinson, Maria I. Chebanenko, Svetlana G. Izotova, Vladimir N. Nevedomskiy, Rufat S. Abiev, Vadim I. Popkov
    Inorganics, 9(5), 39, 2021
    DOI: 10.3390/inorganics9050039
    URL: https://www.mdpi.com/2304-6740/9/5/39
  • Use of Solid Echo Sequence to Monitor Crystallization Kinetics of Mono and Di-Saccharides
    Selen Guner, Leonid Grunin, S. Gulum Sumnu, Mecit Halil Oztop
    Food Biophysics, 16(4), 2021
    DOI: 10.1007/s11483-021-09688-6
    URL: https://link.springer.com/article/10.1007/s11483-021-09688-6
  • A non-conventional TD-NMR approach to monitor honey crystallization and melting
    Berkay Berk, Leonid Grunin, Mecit H. Oztop
    Journal of Food Engineering, 292, 2021.
    DOI: 10.1016/j.jfoodeng.2020.110292
    URL: https://www.sciencedirect.com/science/article/abs/pii/S0260877420303800?via%3Dihub
  • Thermodynamics of Adsorption in a Cellulose–Water System
    Yu.B. Grunin, M.S. Ivanova, D.S. Masas, L.Yu. Grunin
    Russian Journal of Physical Chemistry A, 94(4), 2020.
    DOI: 10.1134/S0036024420040056
    URL: https://link.springer.com/article/10.1134%2FS0036024420040056
  • Features of the Structural Organization and Sorption Properties of Cellulose
    Yu.B. Grunin, L.Yu. Grunin, M.S. Ivanova, D.S. Masas
    Fibre Chemistry, 51(5), 2020.
    DOI: 10.1007/s10692-020-10106-9
    URL: https://link.springer.com/article/10.1007/s10692-020-10106-9
  • Characteristics of Supramolecular Rearrangements in Cellulose in the Processes of its Wetting and Desorption
    Yu.B. Grunin, L.Yu. Grunin, M.S. Ivanova, D.S. Masas
    Fibre Chemistry, 52(1), 2020.
    DOI: 10.1007/s10692-020-10142-5
    URL: https://link.springer.com/article/10.1007/s10692-020-10142-5
  • Cellulose–water system’s state analysis by proton nuclear magnetic resonance and sorption measurements
    Yu.B. Grunin, L.Yu. Grunin, V.Yu. Schiraya, M.S. Ivanova, D.S. Masas
    Bioresources and Bioprocessing, 7(41), 2020.
    DOI: 10.1186/s40643-020-00332-8
    URL: https://link.springer.com/article/10.1186/s40643-020-00332-8
  • Jet-cooked papermaking starches studied using 1H NMR-relaxometry and viscom
    J.P. Raunio, E. Nikolskaya, H. Yrjö
    Nordic Pulp and Paper Research Journal, 2020.
    DOI: 10.1515/npprj-2019-0092
    URL: https://www.degruyter.com/document/doi/10.1515/npprj-2019-0092/html
  • Real-time measurement system for determining metal concentrations in water-intensive processes
    E. Nikolskaya, M. Liukkonen, H. Yrjö
    Open Engineering, 2020.
    DOI: 10.1515/eng-2020-0063
    URL: https://www.degruyter.com/document/doi/10.1515/epoly-2020-0063/html
  • Time-Domain NMR in Characterization of Liquid Fuels: A Mini-Review
    E. Nikolskaya, H. Yrjö
    Energy & Fuels, 2020.
    DOI: 10.1021/acs.energyfuels.0c01464
    URL: https://pubs.acs.org/doi/abs/10.1021/acs.energyfuels.0c01464
  • The use of 1H-NMR Relaxation Times of Water Adsorbed on Soils to Monitor Environment Pollution
    Leonid Grunin, Ekaterina Nikolskaya, John Edwards
    Air, Soil and Water Research, 6(1), 2020.
    DOI: 10.1177/ASWR.S12406
    URL: https://bioone.org/journals/air-soil-and-water-research/volume-6/issue-1/ASWR.S12406/The-use-of-1H-NMR-Relaxation-Times-of-Water-Adsorbed/10.1177/ASWR.S12406.full
  • The Nature of the Supramolecular Structural Variation and Hydrophilic Properties of Cellulose during Water Sorption
    Yu.B. Grunin, M.S. Ivanova, D.S. Masas, L.Yu. Grunin
    Biophysics, 64(6), 2019.
    DOI: 10.1134/S0006350919060071
    URL: https://link.springer.com/article/10.1134%2FS0006350919060071
  • Solids Content of Black Liquor Measured by Online Time-Domain NMR
    E. Nikolskaya, P. Janhunen, M. Haapalainen, H. Yrjö
    Applied Sciences, 2019.
    DOI: 10.3390/app9102169
    URL: https://www.mdpi.com/2076-3417/9/10/2169
  • Molecular Properties of Fatty Acid Mixtures Estimated by Online Time-Domain NMR
    E. Nikolskaya, H. Yrjö
    Applied Magnetic Resonance, 2019.
    DOI: 10.1007/s00723-018-1046-6
    URL: https://link.springer.com/article/10.1007/s00723-018-1046-6
  • Flow Water Proton NMR: In-Line Process Analytical Technology for Continuous Biomanufacturing
    Marc B. Taraban, Katharine T. Briggs, Peter Merkel, Y. Bruce Yu
    Analytical Chemistry, 91, 2019.
    DOI: 10.1021/acs.analchem.9b02622
    URL: https://pubs.acs.org/doi/10.1021/acs.analchem.9b02622
  • Exploring the crystallinity of different powder sugars through solid echo and magic sandwich echo sequences
    Leonid Grunin, Mecit Halil Oztop, Selen Guner, Saadet Fatma Baltaci
    Magnetic Resonance in Chemistry, 57, 2019.
    DOI: 10.1002/mrc.4866
    URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/mrc.4866
  • Dispersion Peculiarities of Crystalline Cellulose Upon its Moistening
    Yu.B. Grunin, L.Yu. Grunin, L.S. Gal’braikh, N.N. Sheveleva, D.S. Masas
    Fibre Chemistry, 49(5), 2018.
    DOI: 10.1007/s10692-018-9890-6
    URL: https://link.springer.com/article/10.1007/s10692-018-9890-6
  • On-line monitoring of cationic starch gelatinization and retrogradation by 1H NMR-relaxometry
    J.P. Raunio, E. Nikolskaya, H. Yrjö
    Nordic Pulp and Paper Research Journal, 2018.
    DOI: 10.1515/npprj-2018-0010
    URL: https://www.degruyter.com/document/doi/10.1515/npprj-2018-0010/html
  • Determination of Carbon Chain Lengths of Fatty Acid Mixtures by Time Domain NMR
    E. Nikolskaya, H. Yrjö
    Applied Magnetic Resonance, 2018.
    DOI: 10.1007/s00723-017-0953-2
    URL: https://link.springer.com/article/10.1007/s00723-017-0953-2
  • Illustration of inversion‐recovery and Carr‐Purcell‐Meiboom‐Gill sequences by the determination of ethanol content in alcoholic beverages
    Yves Gossuin, Quoc L. Vuong, Leonid Grunin, Laurence Van Nedervelde, Anne Pietercelie
    Concepts Magn Reson Part A. 2018. 46A: e21460.
    DOI: 10.1002/cmr.a.21460
    URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/cmr.a.21460
  • Physico-Chemical Changes of Composite Whey Protein Hydrogels in Simulated Gastric Fluid Conditions
    Baris Ozel, Ozlem Aydin, Ozlem Aydin, Leonid Grunin, Mecit H. Oztop
    Journal of Agricultural and Food Chemistry, 66(36), 2018.
    DOI: 10.1021/acs.jafc.8b02829
    URL: https://pubs.acs.org/doi/10.1021/acs.jafc.8b02829
  • The character of changes in the cellulose supramolecular structure during hydration
    Yu.B. Grunin, L.Yu. Grunin, N.N. Sheveleva, S.V. Fedosov, V.G. Kotlov
    Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Teknologiya Tekstil'noi Promyshlennosti, 1(2), 2017. URL: https://www.researchgate.net/publication/321712673_The_character_of_changes_in_the_cellulose_supramolecular_structure_during_hydration
  • An NMR relaxation and spin diffusion study of cellulose structure during water adsorption
    L.Y. Grunin, Y.B. Grunin, E.A. Nikolskaya, N.N. Sheveleva, I.A. Nikolaev
    Biophysics, 62(2), 2017.
    DOI: 10.1134/S0006350917020087
    URL: https://link.springer.com/article/10.1134/S0006350917020087
  • Novel online solution for the measurement of metal ions in water intensive processes
    E. Nikolskaya, M. Liukkonen, H. Yrjö
    Conference: Finnish Conference of Environmental Sciences 2017 (FCES'17) At: Joensuu, Finland. URL: https://www.researchgate.net/publication/317659409_Novel_online_solution_for_the_measurement_of_metal_ions_in_water_intensive_processes
  • Effect of different polysaccharides on swelling of composite whey protein hydrogels: A low field (LF) NMR relaxometry study
    Baris Ozel, Sirvan S. Uguz, Mete Kilercioglu, Leonid Grunin, Mecit H. Oztop
    Journal of Food Process Engineering, 40(3), 2017.
    DOI: 10.1111/jfpe.12465
    URL: https://doi.org/10.1111/jfpe.12465
  • Proton magnetic relaxation study of the thermodynamic characteristics of water adsorbed by cellulose fibers
    Y.B. Grunin, L.Y. Grunin, D.S. Masas, V.I. Talantsev, N.N. Sheveleva
    Russian Journal of Physical Chemistry A, 90(11), 2016.
    DOI: 10.1134/S003602441611008X
    URL: https://link.springer.com/article/10.1134%2FS003602441611008X
  • Structure and Sorption Characteristics of Nanocrystallites of Chitosan
    Yu.B. Grunin, L.S. Gal’braikh, S.V. Levitin, D.S. Masas
    Fibre Chemistry, 48(4), 2016.
    DOI: 10.1007/s10692-017-9785-y
    URL: https://link.springer.com/article/10.1007/s10692-017-9785-y
  • Water Content Analysis of Sludge Using NMR Relaxation Data and Independent Component Analysis
    M. Liukkonen, E. Nikolskaya, J. Selin, H. Yrjö
    Conference: 2016 9th EUROSIM Congress on Modelling and Simulation (Eurosim 2016) At: Oulu, Finland.
    DOI: 10.3384/ecp17142317
    URL: https://ep.liu.se/ecp/article.asp?issue=142%26article=46
  • Free and constrained amorphous phases in polyethylene: Interpretation of 1H NMR and SAXS data over a broad range of crystallinity
    Josef Chmelař, Richard Pokorný, Patrik Schneider, Klará Smolná, Petr Bělský, Juraj Kosek
    Polymer, 58, 2015.
    DOI: 10.1016/j.polymer.2014.12.036
    URL: https://doi.org/10.1016/j.polymer.2014.12.036

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